One of the body reactions which are triggered by androgen therapy results in the body holding too much water than is usually necessary. The resulting turgidity is not beneficial to the body and this is proven by the resulting increase in the risk of circulatory complications such as cardiac arrest. However, no case of pathogenic reactions has been documented as a result of this state of affairs. The level of hematocrit may typically rise but the clinical significance of this state of affairs is highly in doubt.
This, coincidentally, comes as a blessing in disguise because it is a fact that these old men will be expected to be anemic as a result of their hypo-gonadic situation. Anemic symptoms are very common among men suffering from hypo-gonadism. Higher levels of hematocrit help them manage the bouts of anemic attacks by rendering them less lethal.
Another common effect of androgen therapy is the risk of sleep apnea deterioration with continued use of therapy. Changes occur to the tissues at the end of the pharynx. This causes inflammation and this worsens the patient’s conditions. The best way to deal with a man who has a history of sleep apnea and who is scheduled to undergo androgenic therapy is to first deal with and manage the case of the sleep apnea before proceeding with androgenic therapy. There is the risk of imbalances in the level of plasma in the structures of lipoproteins.
There are subtle differences between the hormonal composition in men and women. This has affected the way in which the replacement of testosterone as a form of therapy is carried out. Some physicians ascribe the differing rates of occurrences of incidences of atherosclerotic disease to the hormonal differences between men and women. The evidence for this argument has been more than enough for those who look at the situation from the view point of the changes that occur at puberty. In this case the composition of testosterone is measured at puberty and also after puberty and a comparison is made on the corresponding risk of the disease in both situations, in both men and women.
In men, the levels of the HDL component begin to fall and at the same time when the level of testosterone increases as puberty edges on. The interpretation of these results may vary and there is need, therefore, for a more wide-reaching and conclusive research in to do away with the loopholes that may create an avenue for misinterpretation.
On the contrary, upon looking at men with a hypo-gonadic condition, you will find an array of very conflicting and surprisingly differing results, which, needless to say, attract different conclusions and inferences. These men, in the first place are investigated while undergoing a replacement therapy which involves the use of testosterone. For instance, a recommendation that these drugs should not be administered comes from the consideration of only one side of the findings and may easily and objectively be viewed as unacceptable by many.
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